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Chloroform, or trichloromethane, is an organic compound with formula CHCl3. It is a colourless, sweet-smelling, dense liquid and one of the four chloromethanes and a trihalomethane. It has historical uses as an anesthetic and narcotic sedative, however in the modern era it is more widely recognized as a carcinogen and precursor to phosgene gas. Chloroform has reputedly been used by criminals to knock out, daze, or even murder victims.

Chloroform has been present in a small number of stories by Agatha Christie, among them The Case of the City Clerk and The Adventure of Johnnie Waverly, but has seldom been used.

Characters sedated with chloroform[]

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