The Big Four is an organisation with the goal of world domination. Little is known about the four leaders except:
- Number One is a Chinese political mastermind named Li Chang Yen. He represents the brains of the Big Four.
- Number Two is usually not named but is represented by a '$' or two stripes and a star, so he is probably American and he represents wealth.
- Number Three is a Frenchwoman.
- Number Four is "the Destroyer" and otherwise unknown.
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