Amy Leatheran is a nurse. In Murder in Mesopotamia, she mentions that she did her training at St. Christopher's Hospital, in London, and after that did two years maternity. She did some private work, and then worked for four years at Miss Bendix's Nursing Home at Devonshire Place. When she was in her early 30s she worked in Baghdad, after travelling with an English family there. While in Iraq she met an archaeologist, Dr. Leidner, who employed her to look after his wife Louise.
Nurse Leatheran is thirty-five years old at the time of the events of Murder in Mesopotamia. She is described as having an "erect, confident bearing", and "a good-humoured face with slightly prominent blue eyes and glossy brown hair".
Later she worked as nurse and assistant to Lady Matilda.
In the ITV 2001 TV adapatation of the novel, the part of Nurse Leatheran is played by Georgina Sowerby. She has a significantly reduced role compared with the original novel where she was a first person narrator of the story. Here, many of her roles were taken over by Captain Hastings although she still has many lines and appears in many scenes. Crucially, she sees Anne Johnson holding a piece of paper containing a draft of text which appeared in threatening notes which Louise Leidner had received. From this Nurse Lutheran concluded that Anne Johnson could be the killer and went to Baghdad to report this to Superintendent Maitland and Poirot. Nurse Leatheran also helped Hastings in conducting an experiment to see if a scream from Louise Leidner's bedroom could be heard in the living room. They reported that even a loud scream could not be heard unless the window was open. Poirot thought this finding was interesting, "even illuminating".